Pathogenesis and treatment of type 1 diabetes mellitus

The increased level of glucose is due to some inadequacy in insulin secretion by the pancreas and/or its diminished biological effects (Lonappan et al., 2007). Diabetes, in its extreme, can lead to the death of the patient, but in less severe scenarios it can lead to severe chronic damage and flawed functioning of vital organs such as the blood vessels, heart, eyes, kidneys, and nerves.

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Описание Pathogenesis and treatment of type 1 diabetes mellitus

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Мнение эксперта

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5 окт. 2024 г. · Identify the pathophysiological mechanisms underlying type 1 diabetes, including the role of autoimmune processes and genetic factors, to better inform diagnosis and Автор: Jessica Lucier, Ruth S. WeinstockОпубликовано: 2024/03/03Publish Year: 2025. 15 апр. 2025 г. · This Review highlights knowledge gaps and opportunities to improve the understanding of T1D pathogenesis and outlines emerging therapies to treat or prevent T1D Автор: Alvin C PowersPublish Year: 2025. 20 февр. 2025 г. · Current T1D therapies include insulin, immunomodulatory treatments, organ transplantation, genetic modifications, and others. Type 1 diabetes (T1D) is a complex. 16 апр. 2025 г. · Type 1 diabetes (T1D) is an autoimmune disease characterized by the T-cell-mediated destruction of insulin-producing β-cells in pancreatic islets. It generally occurs in